diff --git a/pandas/tests/io/parser/common/test_file_buffer_url.py b/pandas/tests/io/parser/common/test_file_buffer_url.py
index 4d63a88582fb8..782a75caac0ae 100644
--- a/pandas/tests/io/parser/common/test_file_buffer_url.py
+++ b/pandas/tests/io/parser/common/test_file_buffer_url.py
@@ -93,6 +93,8 @@ def test_nonexistent_path(all_parsers):
     assert path == e.value.filename
 
 
+@td.skip_if_wasm  # limited file system access on WASM, it leads to different
+# error messages than on other platforms
 @td.skip_if_windows  # os.chmod does not work in windows
 def test_no_permission(all_parsers):
     # GH 23784
diff --git a/pandas/tests/io/test_common.py b/pandas/tests/io/test_common.py
index bab2cb1dfa93e..3f7a662fba375 100644
--- a/pandas/tests/io/test_common.py
+++ b/pandas/tests/io/test_common.py
@@ -408,6 +408,7 @@ def test_constructor_bad_file(self, mmap_file):
         with pytest.raises(ValueError, match=msg):
             icom._maybe_memory_map(target, True)
 
+    @td.skip_if_wasm  # limited file system access on WASM
     def test_next(self, mmap_file):
         with open(mmap_file, encoding="utf-8") as target:
             lines = target.readlines()