diff --git a/pandas/tests/scalar/timestamp/test_formats.py b/pandas/tests/scalar/timestamp/test_formats.py
index 6a578b0a9eb09..bc179bb1a2d74 100644
--- a/pandas/tests/scalar/timestamp/test_formats.py
+++ b/pandas/tests/scalar/timestamp/test_formats.py
@@ -6,6 +6,7 @@
 import pytz  # a test below uses pytz but only inside a `eval` call
 
 from pandas import Timestamp
+import pandas.util._test_decorators as td
 
 ts_no_ns = Timestamp(
     year=2019,
@@ -95,6 +96,7 @@ class TestTimestampRendering:
     @pytest.mark.parametrize(
         "date", ["2014-03-07", "2014-01-01 09:00", "2014-01-01 00:00:00.000000001"]
     )
+    @td.skip_if_wasm  # tzset is not available in WASM
     def test_repr(self, date, freq, tz):
         # avoid to match with timezone name
         freq_repr = f"'{freq}'"
diff --git a/pandas/tests/tools/test_to_datetime.py b/pandas/tests/tools/test_to_datetime.py
index 4e8a97701467e..3825b20baf585 100644
--- a/pandas/tests/tools/test_to_datetime.py
+++ b/pandas/tests/tools/test_to_datetime.py
@@ -959,6 +959,7 @@ def test_to_datetime_YYYYMMDD(self):
         assert actual == datetime(2008, 1, 15)
 
     @td.skip_if_windows  # `tm.set_timezone` does not work in windows
+    @td.skip_if_wasm  # tzset is available only on Unix-like systems
     def test_to_datetime_now(self):
         # See GH#18666
         with tm.set_timezone("US/Eastern"):