diff --git a/pandas/compat/__init__.py b/pandas/compat/__init__.py
index 738442fab8c70..c7eeaa5f660bd 100644
--- a/pandas/compat/__init__.py
+++ b/pandas/compat/__init__.py
@@ -21,6 +21,7 @@
     PY311,
     PY312,
     PYPY,
+    WASM,
 )
 import pandas.compat.compressors
 from pandas.compat.numpy import is_numpy_dev
@@ -192,4 +193,5 @@ def get_bz2_file() -> type[pandas.compat.compressors.BZ2File]:
     "PY311",
     "PY312",
     "PYPY",
+    "WASM",
 ]
diff --git a/pandas/compat/_constants.py b/pandas/compat/_constants.py
index 7bc3fbaaefebf..2625389e5254a 100644
--- a/pandas/compat/_constants.py
+++ b/pandas/compat/_constants.py
@@ -17,6 +17,7 @@
 PY311 = sys.version_info >= (3, 11)
 PY312 = sys.version_info >= (3, 12)
 PYPY = platform.python_implementation() == "PyPy"
+WASM = (sys.platform == "emscripten") or (platform.machine() in ["wasm32", "wasm64"])
 ISMUSL = "musl" in (sysconfig.get_config_var("HOST_GNU_TYPE") or "")
 REF_COUNT = 2 if PY311 else 3
 
@@ -27,4 +28,5 @@
     "PY311",
     "PY312",
     "PYPY",
+    "WASM",
 ]