diff --git a/README.md b/README.md index 87da186..f71cf1c 100644 --- a/README.md +++ b/README.md @@ -38,7 +38,7 @@ Usage Support ------- -For user support please email adamscott@wustl.edu +For user support please email amila@wustl.edu Update diff --git a/lib/TGI/Mutpro/Main/Cluster.pm b/lib/TGI/Mutpro/Main/Cluster.pm index 58bc6ec..484bec6 100644 --- a/lib/TGI/Mutpro/Main/Cluster.pm +++ b/lib/TGI/Mutpro/Main/Cluster.pm @@ -80,7 +80,7 @@ sub new { $this->{'linear_cutoff'} = 0; $this->{'max_radius'} = 10; $this->{'length_scale'} = $MAXGEODESIC; - $this->{'vertex_type'} = $SITE; + $this->{'vertex_type'} = $RECURRENCE; $this->{'distance_measure'} = $AVERAGEDISTANCE; $this->{'amino_acid_header'} = "amino_acid_change"; $this->{'transcript_id_header'} = "transcript_name"; @@ -411,7 +411,7 @@ sub setOptions { if ( $this->{'vertex_type'} eq $SITE or $this->{'clustering'} eq $DENSITY ) { if ( $this->{'JSON_status'} == 0 ) { if ( not defined $this->{'hup_file'} or not -e $this->{'hup_file'} ) { - warn "If you're using SITE and/or DENSITY, you must provide a valid hugo.uniprot.pdb.csv file location using --hup-file option\n"; + warn "If you're using SITE and/or DENSITY, you must provide a valid hugo.uniprot.pdb.csv(generated by preprocess step) file location using --hup-file option\n"; die $this->help_text(); } } @@ -2002,7 +2002,7 @@ Usage: hotspot3d cluster [options] OPTIONAL (General) --clustering Cluster using network or density-based methods (network or density), default: network ---vertex-type Graph vertex type for network-based clustering (recurrence, unique, site or weight), default: site +--vertex-type Graph vertex type for network-based clustering (recurrence, unique, site or weight), default: recurrence recurrence vertices are the genomic mutations for each sample from the given .maf unique vertices are the specific genomic changes site vertices are the affected protein positions