Cancer-associated genes analysis of APOBEC motifs

Introduction

This GitHub repository contains scripts to recapitulate all figures and results of the paper. Cytidine Deaminase Under-representation Reporter (CDUR) can be downloaded from the GitLab repository (https://gitlab.com/maccarthyslab/CDUR)¹.

Related work

Song, J. H., Davalos, L., MacCarthy, T., & Damaghi, M. (2023). Evolvability of cancer–associated genes under APOBEC3A/B selection. bioRxiv, 2023-08.

Reference

1. Shapiro, M., Meier, S., & MacCarthy, T. (2018). The cytidine deaminase under-representation reporter (CDUR) as a tool to study evolution of sequences under deaminase mutational pressure. BMC Bioinformatics, 19(1), 163. doi:10.1186/s12859-018-2161-y